The Giovanni Armenise-Harvard laboratory of Immune Regulation, headed by Luigia Pace at IIGM in Candiolo (Turin, Italy), is seeking for a highly motivated and skilled bioinformatician. IIGM (www.iigm.it) is located at the FPO IRCCS Candiolo Cancer Institute, Candiolo, Turin, Italy (www.research.fpoircc.it). The main goal of IIGM is to foster and develop excellence in human genomic research and education, with special reference to genomic variability in multifactorial diseases, with a strong focus on cancer. The institute provides high-level scientific education, and access to state-of-the-art research facilities.
Research: The candidate will spearhead computational and systems immunology analyses in the context of translational and personalized biomedicine, with a strong focus on epigenetics and single cell multi-omics of immune cells.
The Unit addresses fundamental aspects of immune responses, related to memory T cell differentiation and long-term protective immunity. Our research aims to understand how T lymphocytes integrate complex environmental stimuli into specific epigenetic and differentiation programs, which specify cell fate commitment and function. The research’s goal is to use this knowledge to develop novel molecular targets and strategies for the prevention and treatment of cancer in the new field of cancer immunotherapy.
The candidate will combine a variety of high throughput approaches, including next generation sequencing of RNA and epigenetics marks, single cell multi-omics, including the development of new computational pipelines aimed at the integration of different multi-omics.
To apply for this position please submit a cover letter (in English) describing research experiences, interests, motivation, CV and contact information of three references.
Offered contract: post-doc contract or post-graduate fellowship (according to the seniority), 1 year renewable up to 3
Offered positions: no. 01 - available immediately, the call will remain open until it is filled.
References: Pace L, et al. Science 2018; Pace L, et al. Current Opinion Immunol. 2020; Alessandri’, et al. GigaScience 2019; Pace L, et al. Science 2012.